Duodenal Switch - Barbara's WLS Journey & Resources

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About the Duodenal Switch

Restrictive Component
Malabsorptive Component
History of the DS
Published Clinical Data
The DS vs RNY: Differences Between the BPD/DS and the RNY Procedures
Gastric Reduction Duodenal Switch (GRDS) (LGRDS-DS)  
Roux-en-Y / Gastric By-Pass (Open or Laparoscopic) 



Duodenal Switch Procedure

The BPD/DS combines restrictive and malabsorptive elements to achieve and maintain the best reported long-term percentage of excess weight loss among modern weight-loss surgery procedures.


The Restrictive Component

The BPD/DS procedure includes a partial gastrectomy, which reduces the stomach along the greater curvature, effectively restricting its capacity while maintaining its normal functionality.

Unlike the unmodified BPD and RNY, which both employ a gastric “pouch” and bypass the pyloric valve, the DS procedure keeps the pyloric valve intact. This eliminates the possibility of dumping syndrome, marginal ulcers, stoma closures and blockages, all of which can occur after other gastric bypass procedures.

In addition, unlike the unmodified BPD and RNY procedures, the DS procedure keeps a portion of the duodenum in the food stream. The preservation of the pylorus/duodenum pathway means that food is digested normally (to an optimally absorbable consistency) in the stomach before being excreted by the pylorus into the small intestine. As a result, the DS procedure enables more-normal absorption of many nutrients (including protein, calcium, iron and vitamin B12) than is seen after other gastric bypass procedures.


The Malabsorptive Component

The malabsorptive component of the BPD/DS procedure rearranges the small intestine to separate the flow of food from the flow of bile and pancreatic juices. This inhibits the absorption of calories and some nutrients. Further down the digestive tract, these divided intestinal paths are rejoined; food and digestive juices begin to mix, and limited fat absorption occurs in the common tract as the food continues on its path toward the large intestine.

For more detailed procedure information, see Dr. Hess’ patient brochure. For other detailed descriptions and illustrations, see the More Information page for links to surgeon’s websites and more.


History of the DS


The standalone Duodenal Switch procedure (without the accompanying gastric bypass as used in weight-loss surgery) was originally devised by Tom R. DeMeester, M.D. to treat bile gastritis, a condition in which the stomach and esophagus are burned by bile. In 1988, Dr. Douglas Hess of Bowling Green, Ohio, was the first surgeon to combine the DS with the Biliopancreatic Diversion (BPD) form of obesity surgery. This hybrid procedure, known as the Biliopancreatic Diversion with Duodenal Switch (or the Distal Gastric Bypass with Duodenal Switch), solves many nutritional problems associated with other forms of WLS, and allows a magnificent eating quality when compared to other WLS procedures.

source:  http://www.duodenalswitch.com/procedure/procedure.html

 
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Published Clinical Data

Read full text of Hess’ 1998 published report

1.) In 1998, Dr. Hess of Bowling Green, Ohio, published a 10-year follow-up report on the first 440 patients to undergo his BPD/DS procedure (Hess, et al.: Biliopancreatic Diversion with a Duodenal Switch, Obesity Surgery, 8, 1998; 267-282.). This report concludes that this operation has vastly improved the lives of seriously obese patients with many co-morbidities. Furthermore, there has been no late regain of weight in this method.
 

Read full text of Scopinaro’s 1998 published report

2.) The BPD procedure (without the duodenal switch), on which the BPD/DS is based, was first performed in 1976 by Dr. Nicola Scopinaro of Italy. In 1998, Dr. Scopinaro published a 21-year follow-up report on a series of 2241 BPD patients (Scopinaro N, et al.: Biliopancreatic Diversion, World J Surg. 1998 Sep;22(9):936-46. PMID: 9717419; UI: 98383147.). This report concludes that the BPD is the most effective procedure for the surgical treatment of obesity.
 

Read abstract of Marceau’s 1993 published report

3.) In 1993, Dr. Picard Marceau of Laval, Canada, published a report on the benefits of the BPD/DS procedure over the unmodified BPD (Marceau, P., S. Biron, et al. (1993). "Biliopancreatic Diversion with a New Type of Gastrectomy." Obes Surg 3: 29-35.). This report confirms that the DS procedure eliminates or greatly minimizes most negative side effects of the original BPD.
 

Read full text of Rabkin’s 1997 published report

4.) In 1997, Dr. Robert Rabkin of San Francisco, California, published a report comparing results from three procedures including the DGB/DS (Rabkin RA. “Distal gastric bypass/duodenal switch procedure, Roux-en-Y gastric bypass and biliopancreatic diversion in a community practice.” Obes Surg. 1998 Feb;8(1):53-9.44). This report concludes that the DS procedure is an important option for primary treatment of morbid obesity, and that it can be performed safely, with long-term stable weight loss.
 

Read abstract & view summary of results from Marceau’s 1998 report in PDF format

5.) In 1998, Dr. Picard Marceau, et al, published a detailed report on follow-up results from BPD and BPD/DS patients who underwent surgery as far back as thirteen years previously. (Marceau P; Hould FS; Simard S; Lebel S; Bourque RA; Potvin M, Biliopancreatic diversion with duodenal switch., World journal of surgery. 1998 Sep;22(9):947-54). This report summarizes results which illustrate the superiority of the DS enhancement over the original Scopinaro BPD procedure.
 

View Ren, Patterson
& Gagner’s 2000 published report in
PDF format

6.) In December 2000, Drs. Ren, Patterson and Gagner reported on results from their first 40 laparoscopic BPD/DS patients (Early results of laparoscopic biliopancreatic diversion with duodenal switch: a case series of 40 consecutive patients.Obes Surg. 2000 Dec;10(6):514-23). This report concludes that laparoscopic BPD-DS is a complex, yet feasible, procedure resulting in effective weight loss with an acceptable morbidity.
 

View Baltasar’s 20
01 published report in PDF format

7.) In February 2001, Dr. Aniceto Baltasar of Alcoy, Spain published a report on his intermediate results with the Duodenal Switch procedure (“Duodenal Switch: an Effective Therapy for Morbid Obesity—Intermediate Results.” Obes Surg. 2001 Feb;11:54-59). This report found the DS procedure to be very effective for weight control in morbidly obese and super-morbidly obese individuals, with a very satisfactory post-op quality of life.
 

View Baltasar’s 2002 published report in
PDF format

8.) In April 2002, Dr. Aniceto Baltasar of Alcoy, Spain published a report on his early results with 16 Laparoscopic Duodenal Switch patients (“Laparoscopic Biliopancreatic Diversion with Duodenal Switch: Technique and Initial Experience.” Obes Surg. April 2002). This report concludes that LapDS is an advanced, complex and feasible technique in bariatric surgery.
 

View Rabkin’s 2003 published report in
PDF format

9.) In April 2003, Dr. Robert Rabkin, et al, published a report on his laparoscopic technique for performing the Duodenal Switch procedure (“Laparoscopic technique for performing duodenal switch with gastric reduction.” Obes Surg. 2003 Apr;13(2):263-8). This report concludes that this method has yields advantages including decreased pain, improved pulmonary function in the early postoperative period, reduced hospital stay, and a more pleasant cosmetic result.
 

View BPD and BPD/DS related abstracts from Pubmed in PDF format

10.) More clinical data on the Duodenal Switch procedure can be found online at Pubmed by typing “duodenal switch” into search field there. PubMed, a service of the National Library of Medicine, provides access to over 11 million citations from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources.

source: http://www.duodenalswitch.com/procedure/clinical_data/clinical_data.html



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DS vs RNY: The Differences Between the BPD/DS and the RNY Procedures

In researching which type of weight-loss surgery to pursue, people often want to know the differences between the BPD/DS procedure and the more common Roux-en-Y procedure. Several people have written their own comparisons, which are listed below. By reading these folks’ “take” on things, you may gain a greater understanding of exactly how the BPD/DS works.

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By Laura E. in Phillips Ranch, CA

It's not easy to understand the differences between these surgeries! Hopefully, you've had a chance to read up on the ASBS site -- they have a paper there that gives some good info about the various surgeries that are done for obesity. Also, Drs. Anthone and Rabkin have excellent information on their websites that show diagrams and details of the Duodenal Switch procedure. [See the More Information page for these URLs.]

All weight loss surgeries work by making the stomach smaller (restrictive procedures) and/or creating changes in the digestive tract which do not permit the body to absorb all of the fats in the food you eat (called malabsorptive procedures).The DS is a combination restrictive and malabsorptive surgery. The stomach is made smaller and the intestines are rerouted so that you can't absorb all the food you eat. Because of this malabsorption it's essential that you monitor your vitamin levels and take your prescribed vitamins for the rest of your life. It's also the malabsorption that can cause diarrhea if you eat too much fat. The undigested fat in your colon can cause gas problems, but they usually improve in the first 6 months after surgery.

The DS is similar to the RNY with respect to the intestinal bypass (malabsorptive) portion of the procedure. The lower part of this surgery is basically the same as a distal RNY. RNY's are done either proximal (with a shorter length of the intestines bypassed) or distal (with more of the intestines bypassed). Studies have shown that people who have distal bypasses have greater success at losing large amounts of weight and keeping it off.

The RNY and DS are very different with respect to what is done at the top end of the surgery -- the portion involving the stomach (the restrictive aspect of the surgery). The RNY doctors do a variety of things to make the stomach smaller -- most create “pouches” or transect (divide) the stomach. They then reroute the intestines by connecting them directly to the new stomach pouch, bypassing the duodenum. In the RNY/pouch procedures, the pyloric valve (which regulates the emptying of stomach contents into the duodenum) is bypassed and therefore doesn't function after surgery.

In the DS procedure, the surgeon creates a smaller stomach by removing about 75% of the stomach (which is called a partial gastrectomy). The top part of the gastric bypass is connected below the duodenum which keeps the upper part of the digestive process the same as before surgery (except that your stomach is smaller). Your pyloric valve continues to regulate the emptying of the stomach contents into the duodenum and all of the hormones and secretions that occur in the duodenum continue after surgery.

In RNY/pouch procedures, the duodenum and pyloric valve are bypassed and the intestines are connected to the newly created stomach pouch. Dumping happens when the stomach contents (unregulated by the pyloric valve which has been bypassed) dump directly from the new stomach pouch into the intestine. Eating sugars can cause dumping for many RNY/pouch patients. For this reason, they must be very careful of sugars. Some feel that this type of surgery with the dumping syndrome is the best option for people who eat a lot of sweets, since the dumping acts as a deterrent to eating sweets.

Since our pyloric valve and duodenum are left functioning as before, we DS patients don't have dumping syndrome, nor a risk of staple line problems, clogging of the anastamosis, ulcers at the stoma, etc. (remember, we don't have pouches or stomas). So, we don't have the problems with "stretching" the pouch or getting something stuck in the stoma -- because what we have is our real stomach, connected the same way it was before surgery to the duodenum.

Good luck in sorting all of this out!! Of course, I'm biased but I believe the Duodenal Switch is the best surgery for morbid obesity!

Laura E. in Phillips Ranch, CA.
DS/DGB 3-5-99 Dr. Anthone, USC, Los Angeles
Pre-op wt. 418 lbs, 5'7" age 45
Lost 75 pounds as of 4 months post op.

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By Craig in San Francisco

There are always a lot of questions about the difference between the Distal Gastric Bypass with Duodenal Switch (DS) and the more common Roux-en-Y (RNY) procedure. I have done a fair amount of research for myself and can tell you why I have chosen the DS procedure. The following is just my understanding and opinion.

Probably foremost is that the DS avoids altogether the complications with the RNY "anastamosis" -- that is the artificial outlet from the "stomach" pouch into the intestine. Some RNYers have had this opening "close up" on them, sometimes several times. At the very least, this means a very painful trip to the emergency room to have the opening "roto rootered" open again. Unable to eat or even drink water, you can get into trouble quickly.

In the regular RNY, a small pouch is created where the stomach meets the esophagus, and made into a new artificial stomach. The remaining stomach is either stapled off or separated from the pouch. A hole "about the diameter of a pen" is then made in the pouch, and a fresh-cut piece of small intestine is brought up and sewn to that hole.

The opening between the pouch and the intestine is called the anastamosis. Food can block this small opening, or scar tissue can swell it closed. It is also prone to ulcers and bleeding (and internal bleeding is serious), because the "cast iron" tough stomach tissue both is largely impervious to, and itself produces acid, while the tender intestinal tissue sewn to it is neither. [The stomach tissue is a naturally acid environment, while the intestinal tissue is alkaline -- which can make for less-than-chummy bedfellows.]

Another concern is that because the exit from the stomach to the intestine is simply a "hole," from which the stomach contents empty directly into the intestine, it is like a sink whose drain is always open. For this reason, RNY patients sometimes have trouble regulating blood sugar, which causes the very unpleasant "dumping syndrome."

The Duodenal Switch procedure is essentially a newer, arguably more advanced version of the RNY, which avoids all of the above-mentioned problems. DS surgeons are still few and far between. Most DS surgeons have done a many RNYs and have been ultimately dissatisfied with the procedure, which led them to perform the DS.

The DS procedure includes a “distal” gastric bypass, which means that more of the small intestine is by passed than in a "proximal" bypass, which some may worry about. (The RNY can be done with either a distal or a proximal bypass.) The DS’s distal bypass means that fewer nutrients and calories are absorbed than with a proximal bypass. This results in more successful weight loss, but it also means more vigilance is necessary in taking your vitamins and calcium supplements.

[After the DS procedure, patients will continue to absorb sugars completely, so it is important that we consume high-sugar foods in moderation. Proteins and carbohydrates will be absorbed incompletely at first, but the body will acclimate and absorb more of these nutrients with the passage of time.] Fats will never be completely absorbed following the DS, which means that eating high-fat foods can mean smelly and loose bowel movements. (But whose having surgery to keep eating lots of greasy foods?).

The biggest advantage of the DS is that you keep an honest-to-goodness stomach, [which is usually 150-200cc is size (as opposed to the 15-30cc pouch of the RNY)]. The pyloric valve remains intact and functioning just the way God intended it. The pyloric valve is a sphincter muscle that opens and closes to regulate the release of stomach contents into the digestive tract. The retention of the pyloric valve eliminates the dumping syndrome that is experienced by many RNY patients. The DS patient’s stomach can also "churn" food like it is supposed to. DS patients do not have problems with bleeding ulcers or blocked "anastamosis." They are also less likely than RNY patients to vomit unexpectedly.

The bypass portion of the operation is essentially the same as a regular RNY - the top part of one side of the "Y" brings the food down, but has been disconnected from the pancreatic juice and bile. The other top half of the "Y" brings down only that pancreatic juice and bile. They food and digestive juices mix only in the bottom part of the "Y," which results in a greatly abbreviated digestion time.

The RNY is a great operation. It is the one performed by the greatest number of surgeons, and I would not hesitate to undergo it if the DS were not available to me for whatever reason. These surgeries are the best kept secret in medicine, saving lives both figuratively and literally.

Craig in San Francisco
Duodenal Switch 2-9-99, Dr. Rabkin
Pre-op, 410 pounds, 5'13" tall
-100 in 5 months!!!

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Gastric Reduction Duodenal Switch (GRDS) (LGRDS-DS)

This surgical procedure was originated by Douglas Hess, M.D. of Bowling Green, Ohio. In the restrictive component of the LGRDS, 65% of the stomach is resected (removed).  The size of the stomach after resection has the volume for approximately 4-6 oz.

The small bowel (intestine) and duodenum (first segment of small intestine) is divided and new connections are made. This procedure bypasses approximately 60-65 % of the small bowel.  The part of the intestine where the digestion and absorption of fat and proteins is taking place after surgery is called the common channel.

A calculation regarding the length of the common channel is very important in this procedure. It determines how much malabsorption should be created. The length of the small intestine varies for each individual. There are other factors that are also taken into consideration within this calculation. These factors include patient's age, weight, BMI and goals. Each patient has a different length of common channel and alimentary loop designed in order to achieve the best results.

Routinely the gallbladder and appendix are removed. There is a 80 % chance of gallstones forming following weight loss. The gallbladder is removed to eliminate this possibility. The appendix is removed to avoid future confusion of questionable abdominal symptoms of appendicitis or necessity for an appendectomy in the first months following surgery. This type of surgery (LGRDS) is the most successful Bariatric procedure at this time. It is designed to be themost physiological and have the best long term results.

PLEASE NOTE
• no part of the bowel (intestine) is removed in surgery.
• although the stomach is restricted, it will stretch in time. approximately 12 months following surgery patients are able to eat 60 % the amount of food eaten prior to surgery.
• the length of the surgical procedure is 2.5 to 5 hours.
• average hospital length of stay is 3 days.
• weight loss will level out in approximately 12 to 24 months.


RESULTS

Patients are losing 85 % to 95 % of the excess body weight within one to two years following surgery. A patient's weight and BMI prior to surgery does have an effect on the weight loss as well as the compliance of a patient to follow post operative instructions.

Studies have shown that the long term success in this surgical procedure for morbid obesity is approximately 85% of the excess body weight loss. This weight loss has proven to be the most successful for the treatment and alleviation of hypertension, Type II diabetes, sleep apnea, hypercholesterolemia, pain associated with arthritic changes in joints, asthma and urinary stress incontinence as well as improving psycho-social activities.


POSSIBLE SURGICAL COMPLICATIONS


INTRA-OPERATIVE
• bleeding
• blood transfusion
• injury to liver, spleen, esophagus, large bowel

IMMEDIATE POST-OPERATIVE COMPLICATIONS
• perforation involving small bowel, duodenum, stomach
• bleeding
• obstruction
• pancreatitis
• evisceration
• pulmonary emboli
• deep vein thrombosis
• abscess
• pneumonia
• perioperative mortality rate (approximatey 0.5%)

SUBSEQUENT POST-OPERATIVE LONG TERM COMPLICATIONS
• hernia
• excessive weight loss
• osteopenia / osteoporosis
• anemia
• obstruction

 

SYMPTOMS TO RECOGNIZE

Side effects following this surgery are very rare, however, patients sometimes do experience various symptoms. The most typical symptoms are distorted taste and smell, dry mouth, diminished appetite, occasional nausea, dizziness and hot flashes. Most patients discover these symptoms are gone within 2 - 4 weeks after surgery.

The symptoms patients need to be aware of that are of most concern are frequent nausea with vomiting, diarrhea, temperature above 100 degrees, drainage from incision, unexpected abdominal pain, shortness of breath, chest pain or swelling of the legs.

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Roux-en-Y / Gastric By-Pass (Open or Laparoscopic)

Roux en Y (RNY) or gastric bypass is a restrictive procedure that staples off an approximate 5-35cc stomach pouch at the upper portion of the stomach. A section of small bowel is then attached to the pouch via a small opening.

Narrowing and or blockages can take place at this small opening. Ulceration can also happen at the area where the small bowel and the stomach tissue are attached.

Due to the small pouch size vomiting can take place if food is not properly chewed or food is eaten too fast or in too large a volume. 

Dumping syndrome also takes place when consuming high sugar food.

When the opening in between the pouch and the small bowel is stretched patient begins to regain weight. This generally occurs approximately 2 years after surgery

 


 

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