Duodenal Switch - Barbara's WLS Journey & Resources

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Which Procedure Is Right For You?


Anatomic, Physiologic and Patient considerations in selecting the appropriate intervention for patients with morbid obesity:

The most important factor in achieving success in bariatric surgery is patient selection and intervention selection. Most patients who present for evaluation for bariatric surgical procedures are self-referred, determined to achieve change, and willing to make personal life-long sacrifices to achieve their goals. Candidates who are not self-referred, reluctant, uncertain, and attached to certain eating behaviors are to be counseled extensively before proceeding to surgery. Once you have determined that the patient is in the first of the above two categories, or after extensive counseling, therapy as needed, and appropriate time you have succeeded in establishing that the patient belongs to the former category, the next step is education.


Education:

Anatomic and Historically Known Considerations:

Click here to view anatomy of the stomach

The esophagus is the first passageway into the stomach. History tells us that interventions above or at the level of the esophagus are not effective for the treatment of morbid obesity. For example, wiring the teeth shut is ineffective because the patient's nutritional source is liquid and shakes. Rapidly, patients consume such high calorie liquids and reach their homeostatic or baseline level of nutritional intake and therefore do not loose weight. The Angelchick prosthesis of the past taught us that obstructive devices on the esophagus were frought with complications such as erosion, and esophageal dilation and are therefore not an option.

The EG junction and its physiologic function to relax for food passage and tighten to prevent reflux is important. In patients with significant reflux disease, certain operations should be avoided.

The fundus of the stomach has a thin wall and a great propensity to stretch. Prior historical experience tells us to avoid using this portion of the stomach in the formation of a pouch because of this propensity.

The body of the stomach produces acid and has muscular digestive function as well for mixing chyme.

The lesser curvature of the stomach is the thicker walled portion of the stomach, has lesser propensity to stretch, and is more fixed in position.

The pylorus is the outlet of the stomach and is important in regulating the output of the stomach so as to properly limit acid output to the duodenum, control chyme and other fluid output from the stomach, and prevent bile reflux between meals. Denervation of the pylorus results in spasm and obstruction here, and disabling (pyloroplasty or pyloromyotomy) or bypassing the valve (as with the Roux-en-Y Gastric Bypass - RNY-GB - procedure) results in dumping syndrome because of unregulated emptying of high solute concentration liquids (specifically sweets) into the small bowel.

The antrum is the lower 1/3 of the stomach. It is important for two main reasons. First, it harbours G cells that secrete gastrin. This is a paracrine and endocrine hormone that stimulates acid production. This is important when considering the larger pouch of the Scopinaro BPD where the endocrine gastrin effects can increase pouch acid production and increase the rate of ulceration. This is why a distal gastrectomy is recommended with larger pouch procedures.

The acid is also important when considering the duodenal switch procedure where preservation of antral acidification helps convert dietary iron to its absorbable oxidized ferric form. Parietal cells in the antrum also produce an intrinsic factor, a protein necessary for B12 absorption in the ileum.

The duodenum is important in the secretion of a number of hormones including secretin, cholecystokinin, and enteroglucagon. Leaving the duodenum within the digestive food channel is believed to allow for more normal GI hormonal response to meals which is felt to provide improved physiologic response to meals and improved satisfaction.

The bile duct, main pancreatic duct and accessory pancreatic ducts are shown to illustrate the anatomic and surgical hazards associated with performance of the duodenal switch procedure, and to allow for an understanding of its mechanism. The portions of the small bowel are shown with their approximate lengths (unstretched) to allow also for understanding the lengths of intestinal tract used in various parts of the available surgical procedures.


The Simplified Basics of Weight Balance:


The concept of weight balance or caloric equilibrium is based on the concept of basal metabolic rate mandating that each individual has a certain daily caloric need that will result in neither weight gain (anabolism) nor weight loss (catabolism). For most people this is about 1800 calories per day. For some it is lower, for others higher.

Patients who have gained excess body weight, have done so by caloric intake that exceeds their daily caloric need on a daily basis for a sustained period of time. If weight gain is on-going, then this excess intake is on-going. Weight loss requires that intake (and/or absorption of intake) be reduced below metabolic need on a daily basis for a sustained period of time.

Balance is reached by this process when the patient's total body size now requires less calories for maintenance, and that need is met by the intake and absorption that the patient is capable of achieving post-operatively. Weight loss therefore stops at this equilibrium.

How then do we reduce the caloric intake of the patient? The best approach is to determine where the EXCESS calories are coming from and eliminate (restrict) that source or prevent that source of excess calories from being absorbed (malabsorption). In order to target these sources, we attempt to categorize patients' excess caloric intake sources.

These excesses are categorized as follows:

1) "Bloating": over-eating, eating large meals

2) "Grazing": constant snacking during the day and between meals or at night.

3) "Sweeting": frequent ingestion of high calorie simple sugar containing foods/drinks/shakes

4) "Choosing": choosing the wrong foods at each meal (high fat, fried, high carbohydrate, low fiber)

Patients are then asked to classify themselves to determine where their excess calories have come from. If the patient reports that they do not get excess calories currently, then when they were getting excess calories, where did they come from in the past. Most patients can classify themselves into one or two of the above categories, for the most part. Patients who report that they have had stable weight for over one year, are likely to be no longer eating excess calories but rather have truly modified their diets to reach balance. These patients are classified as normal to low metabolizers depending on their reported caloric intake.

The first step in selection is education. The best judge of the patient's need is the patient. The only limiting factor is the patient's knowledge base. Once the patient determines their classification, then an effective procedure can be chosen. This process is accomplished with the patient. Other factors that play into the decision include the patients weight loss goals, short and long-term risk tolerance, and side-effect tolerance.


Flow Chart of Decision making:

Condition & Surgical Choice


Bloater
Choose: VBG, AGB, VG-Sleeve, or PRYGBP

Grazer
Avoid: VBG, AGB, VG-Sleeve Avoid: PGBP
May Choose: BPD, BPD-DS, MGBP, DGBP

Sweeter
Avoid: VBG, AGB, VG-Sleeve
May Choose: GBP, BPD, or BPD-DS

Chooser

May Choose: BPD or BPD-DS, MRYGBP, DGBP
Low Metabolizer
May Choose: BPD or BPD-DS, MGBP, DGBP

Weight loss goal 60-65%
May Choose:
PRYGBP, VBG, VG-Sleeve, AGB

Weight loss Goal 70-80%

May Choose: MRYGBP, BPD or BPD-DS

Weigh Loss Goal 90-100%
May Choose: DGBP at 1-2 years, BPD or BPD-DS at 3-4 yrs

Accepts High (10% -20%) long term risk of Vitamin or Protein Malnutrition
May Choose: DRYGBP

Accepts Moderate (5-7%) long term risk of Vitamin or Protein Malnutrition
Choose: BPD or BPD-DS

Desires Low (1-2%) long term risk of Vitamin or Protein Malnutrition
Choose: PRYGBP

Desires No (<1%) long term risk of Vitamin or Protein Malnutrition
Choose: AGB, VG-Sleeve, or VBG

Chronically Iron deficient
Avoid all GBP and avoid BPD-Scopinaro
Choose BPD-DS

Osteoporosis or strong family history of this or at risk for this
Avoid BPD-Scopinaro and BPD-DS

Cannot accept weight regain risk of 20% at 3 years
Avoid PRYGBP


Abbreviations:

AGB

Adjustable Gastric Band

GBP
Gastric Bypass

M
Middle

D
Distal

BPD
Biliopancreatic Diversion

DS
Duodenal Switch

VBG
Vertical Banded Gastroplasty

VG/SG (or VG-Sleeve)
Vertical Gastroplasty with Sleeve Gastrectomy (Also known as Magenstrasse-Mill Operation)

P
Proximal Roux-en-Y

BPD-DS
Biliopancreatic Diversion with Duodenal Switch (performed in conjunction with Vertical Gastroplasty with Sleeve Gastrectomy)

EBWL
Excess body weight loss.


[i] (Cowan 1996), (Abu-Abied 2001), (Deitel 1999), (Glenny 1997).

[ii] (Macgregor 1998).

[iii] (WHO 1997).


source:  http://www.alagsa.com/Bariatric_Surgery.htm